Mascot: The trusted reference standard for protein identification by mass spectrometry for 25 years

Posted by Web Master (March 31, 2022)

Mascot Server 2.8.1 patch release

Mascot Server 2.8.1 has been released. Updates from 2.8.0 for both Windows and Linux can be downloaded from the support page.

This patch release includes several important bug fixes and changes. The full list is available on the support page. Highlights include:

  • 13874: Mascot cannot use NCBI nr larger than about 370 million sequences
  • 13202: NCBIprot takes approximately 50 times longer than TrEMBL to compress
  • 12837: Update mzIdentML export to 1.2
  • 13346: Add support for semi-specific enzymes in crosslink searches
  • 13963: Add TMTpro 18plex quant method
  • 13964: Add EAD as new instrument type

Bug fix 13874 requires recompressing all databases including NCBIprot. Recompression will happen automatically after the update has been installed. It is best to schedule a suitable amount of downtime.

Please do not hesitate to contact us with any questions.

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