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Posted by Richard Jacob (September 16, 2020)

The minutiae of database management

The two major inputs into a database search are sequence databases and mass spectrometry data. Management of the databases in Mascot Server has evolved and improved over the years and newer versions. There are still a few issues that come up regularly and I am going to cover them in this article. Common error messages When you activate a new [...]

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Posted by Ville Koskinen (March 20, 2020)

How to set up remote working

There are times when you unexpectedly find yourself having to work from home. Fear not: data analysis doesn’t need to stop when you’re away from the lab. Mascot Server has a client-server architecture, and the client PC can be located anywhere. Distiller and Daemon can also be used remotely, or they can be run on a remote client PC and [...]

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Posted by Richard Jacob (November 18, 2019)

Disaster recovery

There are a number of potential issues that can cause your Mascot Server or other computer infrastructure to stop working. In the worst case, you may need to do a full recovery from backups. This can be an involved procedure, but it is straightforward as long as you have backed up key configuration and data files. For disk or storage [...]

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Posted by John Cottrell (June 27, 2014)

Spring clean your mascot.dat

Updates to Mascot 2.5 will be going out shortly. When an existing installation is updated, settings in the options section of mascot.dat are only modified by the installer in exceptional cases. The assumption is that any changes have been made with good reason and should be honoured. The down-side of this approach is that values may be persisted that are [...]

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Posted by David Creasy (June 17, 2013)

Backing up your Mascot Server

The demise of Tranche, last year, with reports that 80% of the raw data ‘safely held’ there has been permanently lost, should be a wake-up call for many laboratories to consider their back up strategy. It’s very hard to get reliable data for the annualised failure rate (AFR) of disk drives, but most estimates suggest around 1.5% of drives will [...]

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Posted by John Cottrell (February 1, 2013)

Don’t get stuck in a queue

Mascot Server doesn’t queue searches. This isn’t because we can’t be bothered to write the code. Its because we don’t believe queuing would improve performance or usability. The times taken for individual searches cover a very wide range. A PMF or a small MS/MS search with few variable modifications and tryptic specificity might take seconds. A large MS/MS search of [...]

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