
Mascot Distiller download
Mascot Distiller 2.8
The latest version is Mascot Distiller 2.8.
- Download Mascot Distiller 2.8 installer (341 MB). Choose either to “Run this program from its current location” or “Save this program to disk”, then execute it. The installer is signed by Matrix Science Ltd.
- If you are installing Distiller for the first time, it will prompt you for a product key. Follow the instructions to register your product key online.
Updates for Mascot Distiller 2.7 and earlier
Updates from earlier versions to Mascot Distiller 2.8 are currently free. You should download and install this free update.
- Download Mascot Distiller 2.8 installer (341 MB). Choose either to “Run this program from its current location” or “Save this program to disk”, then execute it. The installer is signed by Matrix Science Ltd.
- Your existing product key remains valid and you do not need to register a new one.
System requirements
Mascot Distiller integrates with Mascot Server for protein identification by database searching. We recommend the latest release of Mascot Server. Batch automation of quantitation requires Mascot Daemon, which is shipped as part of Mascot Server.
Mascot Distiller requires 64-bit Microsoft Windows 10 or later, Server 2016 or later. Distiller is fully compatible with Windows 11/Server 2022/Server 2025. In all cases, the latest service pack should be applied. Mascot Distiller requires .NET Framework 4.7 or later to run.
For PC hardware, we recommend an Intel Core i9 or AMD Ryzen 9 processor with at least 16 cores, 32GB RAM (preferably 64GB) and fast disk with at least 4TB of space. NVMe is recommended. Distiller does not use a GPU; all computation is done on the CPU.
Evaluation
Mascot Distiller is available as a 30-day free trial.
