Mascot: The trusted reference standard for protein identification by mass spectrometry for 25 years

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Archive

Date Topics  
September 2024 • Machine learning in Mascot Server 3.0
• Untargeted identification of viruses
• Preorder Mascot 3.0 now
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August 2024 • 30 years of Sequence Tags
• Proteomics of peanut allergens
• Error tolerant sequence tag example
English
Japanese
Chinese
July 2024 • Mascot workflow for LC-MS/MS
• Adaptive epigenetic changes in histone variants
• Free temporary licence for migration
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June 2024 • Breakfast meeting summary
• Mascot at ASMS 2024
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Chinese
May 2024 • ASMS User Meeting
• Optimizing sample preparation with an artificial neural network
• Free Mascot service
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April 2024 • ASMS User Meeting
• Wind effect in plant protein expression
• New distributor in Europe
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Chinese
March 2024 • Guest user settings
• Impact of software on fast photochemical oxidation of protein (FPOP) analysis
• Mascot for your research lab
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February 2024 • Unsuspected mods with DIA
• Spatial heterogeneity of uterine cancer tumors
• Deleting obsolete predefined definitions
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Chinese
January 2024 • Narrow window DIA
• Ubiquitylation and DNA damage response
• Windows Server 2019
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Chinese
December 2023 • ABRF Crosslinking Study
• N-terminal acetylation shields proteins from degradation
• Internal fragments with HCD
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Chinese
November 2023 • Chimeric spectra
• Characterizing Shewanella integral membrane complex
• Mascot Distiller 2.8.5
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Chinese
October 2023 • Distiller’s 20th anniversary
• LAP-MALDI MS for detection of bovine tuberculosis
• Automated Distiller reports
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Chinese
September 2023 • Software version numbers
• Mapping the human chondroitin sulfate glycoproteome
• Mascot Server 2.8.3
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August 2023 • Optimise your chunk size
• Sequencing isomeric proteoforms using cyclic ion mobility and ECD
• Mascot Distiller 2.8.4
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July 2023 • Creating DIA spectral libraries
• Mass spectral analyses of Salmonella myovirus
• Crosslinking with DSSO
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June 2023 • User meeting slides
• Mascot posters at ASMS
• Updated training materials
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May 2023 • Breakfast meeting at ASMS
• High-throughput venomics
• Mascot in the Cloud
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Japanese
April 2023 • Breakfast meeting at ASMS
• Bioinertization of nanoLC/MS/MS systems for phosphoproteomics
• 25 years of Matrix Science
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March 2023 • Crosslinked peak picking
• Targeted protein dephosphorylation
• Batch scripting with Distiller
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Japanese
February 2023 • Paleoproteomics
• Biomarkers in the exosome of endometrial cancer serum
• Staying up to date
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January 2023 • Complementary reporter ions
• Growing ryegrass on Martian regolith simulant
• Free disk space
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December 2022 • Distiller quant reports
• Tubulin glutamylation and glycylation
• TMTpro quant methods
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November 2022 • Trusting your search engine
• Temporal phosphoproteomics of EV-A71-infected cells
• Virtualisation
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October 2022 • Fractionated LFQ
• PMF of preserved collagen in archaeological fish bones
• System limits on Linux
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September 2022 • mzIdentML 1.2
• Biomarkers of residual malaria parasites
• Mascot Server 2.8.2
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August 2022 • SARS-CoV-2 spike protein disulfide bonds
• Protein products of non-coding transcripts
• Disaster recovery
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July 2022 • Single-cell spectra
• VAMS-Trypsin immobilization for instant proteolysis
• New pricing for updating old licences
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June 2022 • ASMS presentations
• Identification of Protein Isoforms using RNA-seq reads
• False Discovery Rates
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May 2022 • ASMS User Meeting
• Peak picking with Distiller
• Androgen receptor interactions
• Glycans in Unimod
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April 2022 • ASMS User Meeting
• NCBI nr tips
• Filter-aided sample preparation
• Mascot Server patch
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March 2022 • Linux cluster security
• Glycation in milk
• EST Fasta files
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February 2022 • FTP retirement
• Histone code of the malaria parasite
• Mascot Distiller update
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January 2022 • Hardware for Mascot Distiller
• Serological testing for SARS-CoV-2
• Making Protein Family Summary the default report
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December 2021 • Endogenous peptides
• Solid phase extraction
• Mascot Daemon housekeeping
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November 2021 • ASMS 2021 presentations
• 3D bioprinted tumor models
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October 2021 • Disk bottlenecks
• N-terminally ubiquitinated proteins
• Local vs. public modifications
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September 2021 • Error tolerant search statistics
• Anti-bacterial peptides
• Exporting ion mobility values
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August 2021 • Ion mobility filtering
• Proteomics of Primary Uveal Melanoma
• Mascot Server 2.8 release
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July 2021 • LFQ with Mascot Distiller 2.8
• Mapping proximity associations
• Retention time in Percolator
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June 2021 • Counterfeit cashmere
• Protein carriers
• Mascot Server 2.8
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May 2021 • Unipept for taxonomy assignment
• Extracellular matrix proteome
• Mascot Distiller 2.8
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April 2021 • Updated NIST Human spectral libraries
• Histone methylation profiling
• Standard enzyme definitions
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March 2021 • Sizing a Mascot Server license
• Collagen in Ancient Bone
• NCBI nr alternatives
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February 2021 • Single Sign-On
• Zirconium-IMAC
• Variable modification tuning
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January 2021 • de novo Competition Results
• Automated plasma proteome preparation
• Cross-link modification
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December 2020 • de novo Competition
• Database management
• ADP-ribosylated peptidesk
• Spectral quality tutorial
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November 2020 • Crosslinked peptide ID
• Enriching N-terminal peptides
• Client error message quirk
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October 2020 • Quantitation charts and plots
• Sialylation in rat nerve terminals
• Custom and predefined database configurations
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September 2020 • Variable modifications
• Aberrant N-glycosylation
• Support and update reminder
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August 2020 • Summarizing quantitation data
• Host cell proteins in biopharmaceuticals
• Database Manager error message
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July 2020 • Human Proteome Project Guidelines
• Cysteine quantitation
• Creating new crosslinking methods
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June 2020 • ASMS Reboot Presentations
• Quantitation p-values
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May 2020 • Remote working
• Shotgun proteomics of SARS-CoV-2
• Finding help topics
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April 2020 • Protein FDR
• N-term Arg and Lys enzyme
• New databases on public server
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March 2020 • Disaster Recovery
• In-line sample preparation
• Spectral library creation
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February 2020 • Search reproducibility
• Ion mobility separation of proteoforms
• Modifications in spectral libraries
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January 2020 • Mascot Server 2.7
• mAb sequence validation
• Uniprot proteomes
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December 2019 • Protein scores
• Persulfidation
• Access database engine
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November 2019 • Diethylation
• Ionic liquid-based sample preparation
• IIS configuration
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October 2019 • Shared peptides
• Palmitoylation And Nitrosylation Interplay Monitoring
• Fixed and variable modifications
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September 2019 • Benchmarking protein inference
• Photosynthetic apparatus of Pinaceae
• Controlling search priorities
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August 2019 • Peptide-spectrum match statistics
• Epitope mapping by direct nano-electrospray MS
• Windows versus Linux version of Mascot
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July 2019 • Proteome Discoverer workflows
• Summed intensities improve iTRAQ accuracy
• Neutral loss configuration
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June 2019 • Metaproteomics with Mascot
• Middle-Down searching
• Exclusive mods, combination mods, metabolic labelling
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May 2019 • ASMS User Meetings 2019
• Daemon automation
• Analysis of C Terminome
• Distiller quantitation speed-up
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April 2019 • ASMS User Meetings 2019
• X!Hunter spectral libraries
• Identification of PEG-based detergents
• Combining Mascot Server licences
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March 2019 • Proteomic Forum 2019
• O-glycosylated peptides
• Adsorption-based sample preparation
• Capturing error messages
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February 2019 • Use spectral libraries today
• High-resolution spatial proteomics
• Enzyme mixtures
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January 2019 • 1 Da modifications
• Unexpected modifications
• Using Report Builder
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December 2018 • Quantitation statistics
• Single Amino Acid Variant discovery
• De-charging a peak list
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November 2018 • Mascot Server cluster mode
• Ion suppression in phosphoproteomics
• Rebuilding the search log
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October 2018 • Common mistakes
• Deep dive on human CSF
• Troubleshooting corrupt XML
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September 2018 • Search parameter optimization
• Identifying proteins in ancient paintings
• NCBIprot maximum sequence length
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August 2018 • Free consultations at HUPO
• Mascot Distiller speed
• Fibronectin Proteolysis
• Filtering out short peptides
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July 2018 • HUPO consultation sessions
• Quantitation of cysteine oxidation
• Catechol Estrogens
• Editing the Mascot Daemon task database
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June 2018 • Genome database updates
• Determination of site-specific phosphorylation ratios
• Troubleshooting Mascot Daemon
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May 2018 • ASMS User Meetings
• HTTPS Issues
• Mining the human tissue proteome for protein citrullination
• Mascot Server 2.6.2
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April 2018 • 20-20 Special Offer
• ASMS Workshops
• MS3 Reporter Ions
• Tip-based identification of protease substrates
• Mascot Distiller 2.7
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March 2018 • 25 years of protein ID
• Glycopeptide identification
• PC hardware specification
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February 2018 • Dark matter challenge results round-up
• Biomarkers for Alzheimer’s
• Model Distiller project
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January 2018 • Shared task database
• Peptide biomarkers for ovarian cancer
• UniProt reference proteome
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December 2017 • Alkylation issues
• Detergents for Membrane Protein Complexes
• Controlling running searches
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November 2017 • Contaminants spectral library
• Non-canonical phosphorylation
• Excluding modifications from error tolerant search
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October 2017 • Trypsin autolysis
• Kinase activity ranking
• Disabling cache files
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September 2017 • Which ions series?
• SLIM labelling
• Modifying the taxonomy tree
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August 2017 • Mascot security
• Protein N-term characterization
• Quantitation of extreme ratios
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July 2017 • Dark matter challenge
• Alkylation side-effects
• Anti-virus advice
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June 2017 • Exporting search results
• Detection of methicillin-resistant S. aureus
• Housekeeping automation
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Japanese
May 2017 • ASMS breakfast meetings
• Peak lists
• Giant Buddhas
• Reporting combined results
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April 2017 • ASMS breakfast meetings
• Protein FDR
• Protein carbonylation
• Adding a new element
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March 2017 • Proteomics repositories
• Trace-level residual proteins in human Ig
• Processing options files in Mascot Distiller
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February 2017 • Chimeric spectra
• Yeast small subunit processome
• Initiator Met
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January 2017 • Retention Time in Mascot
• The Protein Co-Migration Database
• Why summary reports no longer show non-significant matches
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December 2016 • Spectral library searching
• The epichaperome
• Mascot Daemon 2.6
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November 2016 • Hardware for Mascot Server
• Proteasome-generated spliced peptides
• Very long sequences
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October 2016 • Multiple fragmentation methods
• Phosphoproteomics of Flu
• Ambiguous residues
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September 2016 • High FDRs for methylated peptides
• Protein primary structure of the Vaccinia virion
• NCBI have dropped gi number identifiers
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August 2016 • HUPO 2016
• mzTab export
• HLA-DR bound peptides
• Negative ions
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July 2016 • Unlabelled peaks
• Bacterial Interactomes
• Peptide charge state
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June 2016 • Mascot Distiller 2.6
• Circadian clock proteins
• Mysterious crashes
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May 2016 • ASMS breakfast meetings
• Selenocysteine and U
• Tetracycline-inhibited ribosome profiling
• The database *.stats file
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April 2016 • ASMS breakfast meetings
• ETD analysis of Histone Proteoforms
• Web server timeout
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March 2016 • Search only for peptides we care about
• Cryo-slicing Blue Native-MS
• YouTube video
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February 2016 • Quality assurance
• Histone PTMs
• Command line search
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January 2016 • Listing confidently identified proteins
• California sea lion CSF
• Introductory tutorials
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December 2015 • Baker Street
• Methionine Sulfoxide Dynamics
• Distiller project viewer
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November 2015 • Mass-tolerant search
• S-glutathionylation
• CID+ETD Instrument
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October 2015 • De novo sequencing
• Giant virus from permafrost
• Intensity values for components
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September 2015 • Mascot Distiller
• Microbial antigen typing
• Customizing modifications
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August 2015 • Search with ESTs
• Identification of Regulatory and Cargo Proteins
• Mascot Security
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July 2015 • How do I do that?
• Enrichment of Vesicular Glycoproteins
• Webcast training course updated
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June 2015 • Mascot Server in "The Cloud"
• Online Peptide Fractionation Using an LC-chip
• Mascot tip – Auto-export in Mascot Daemon
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May 2015 • ASMS User Meeting
• Site analysis
• Global Analysis of Myocardial Peptides
• Mascot tip – Glycopeptide analysis
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April 2015 • ASMS User Meeting
• Mascot on a virtual machine
• Phospho-iTRAQ: Assessing Isobaric Labels for the Large-Scale Study Of Phosphopeptide Stoichiometry
• Mascot tip – Migrating to new hardware
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March 2015 • DIA-Umpire enables database searching of DIA data
• The first step of peptide selection in antigen presentation by MHC class I molecules
• Mascot tip – Peak list re-centroiding
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February 2015 • Quantify then identify or identify then quantify?
• Deciphering Preferential Interactions within Supramolecular Protein Complexes: the Proteasome Case
• Large Scale Proteomics symposium at Proteomic Forum 2015
• Mascot tip – Mascot Daemon data import filters
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January 2015 • The true benefit of high mass accuracy
• Rapid Identification and Quantitative Validation of a Caffeine-Degrading Pathway in Pseudomonas sp. CES
• Large Scale Proteomics symposium at Proteomic Forum 2015
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December 2014 • Why can’t I search with more than 9 variable modifications?
• Targeting Synaptic Pathology with a Novel Affinity Mass Spectrometry Approach
• New patch for Mascot Server 2.5
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November 2014 • How long should my search take?
• Tracking Cancer Drugs in Living Cells by Thermal Profiling of the Proteome
• Mascot Server 2.5 now available
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