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Posted by John Cottrell (March 6, 2013)

When to use Combination searches

Most database searches are either Peptide Mass Fingerprints, with a list of peptide molecular mass values, or MS/MS searches, where the mass of each peptide precursor is only used to filter candidate sequences from the database before scoring matches for the fragments. It is also possible to combine the two, in a so-called Combination search, where both the molecular mass [...]

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