Mascot: The trusted reference standard for protein identification by mass spectrometry for 25 years

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Posted by Ville Koskinen (November 16, 2021)

Retiring the File Transfer Protocol (FTP)

Mascot Server includes Database Manager, which can be configured to download protein sequence databases from many sources using FTP (File Transfer Protocol), HTTP (Hyper Text Transfer Protocol) and HTTPS (HTTP Secure). FTP is the oldest of these protocols by far, making its first appearance in 1971. Until some years ago, FTP was the best and only choice for large file [...]

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Posted by John Cottrell (March 14, 2018)

Stepping up security

In late 2016, NCBI dropped support for HTTP requests and restricted their web resources to HTTPS. EBI went HTTPS by default in October 2017 and UniProt has announced that it will go HTTPS-only in June 2018. The UniProt change will cause a problem with Database Manager in older versions of Mascot. This article summarises the effects of turning off HTTP, [...]

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