New features in Mascot 2.3
Protein Family Report
The Protein Family Summary displays search results a page at a time, allowing the results of even the largest searches to be browsed without client-side memory or browser limitations. Proteins are grouped into families using hierarchical clustering, making protein inference more intuitive and more accurate.
Percolator Support
Percolator is a utility from the University of Washington that uses machine learning to re-rank the peptide matches. The goal is to maximise sensitivity for a given false discovery rate.
Search Multiple Databases
Multi-select more than one database for a search. This is useful when you want to search a single organism database and include the sequences of common contaminants, such as BSA and trypsin.
Other important changes
- Export search results as mzIdentML
- Batch automate quantitation with Mascot Daemon
- Support for mzML format peak lists
- 64-bit executables for Windows.
- Result report caching makes all large reports faster to load
- Support for Perl 5.10.
- Multiplex quantitation now supports isobaric precursors.
- Reports now show counts of distinct sequences as well as counts of matched spectra.
- … and lots more